The Islets of Langerhans

The Islets of Langerhans

"A very timely book"

READ THE BOOK ONLINE. This book is a unique and thoughtful blend of critical background information and advances made in a multitude of areas of contemporary islet research.

It is an essential reference book, the first of its kind in many years, for professionals as well as for the beginners interested in the study of islet physiology and diabetes. The book is unique in its breadth: it deals with anatomy, histology, ultra-structure, evolution and comparative anatomy, imaging, developmental biology, programming, apoptosis, mitochondrial function, metabolism, cellular signaling, electrophysiology, oscillation of hormone secretion, islets of model animals, immunology, proteomics, regenerative medicine, clinical advances, islet transplantation, and finally islet tumors. Individual chapters contributed by over a hundred experts and enthusiasts, not only provide a balanced view of the recent advances made in the respective fields, but also provide directions and thoughts for future research. Thanks to vivid and colorful illustrations, tables and sketches, the book as a whole, and the individual chapters make reading a pleasant experience. It is a valuable compilation that one would love to possess personally and buy as a present to a colleague. 820 pages, 34 chapters, 91 authors, 111 figures. Please click here to get your copy from Amazon.com

Reviews of "The Islets of Langerhans"

ReviewsPosted by Md. Shahidul Islam Thu, January 07, 2010 09:16:36

"A very timely book on the Islet of Langerhans that coincides with the realization that pancreatic ß-cell failure is key to all forms of diabetes mellitus and research in the field is exploding. It contains very thoughtful chapters, each by renown experts in their field, and tackles the complexity of this micro-organ in health and disease very comprehensively and thoughtfully. It will likely become a Reference for years to come for basic researchers, clinicians and students interested is diabetes research". Marc Prentki, PhD, Professor of Nutrition and Biochemistry, Canada Research Chair in, Diabetes and Metabolism, MDRC Director

"The pancreatic islet is a complex mini-organ whose dysfunction is critical in all forms of diabetes. This book provides a comprehensive review of the molecular and cellular processes in islet development, gene expression, and physiology and reviews how a better understanding of the pancreatic islet will advance efforts to develop new therapeutic approaches for diabetes. This book should be quite useful for anyone interested in the pancreatic islet or diabetes". Alvin C. Powers, M.D., Joe C. Davis Chair in Biomedical Science, Professor of Medicine, Molecular Physiology and Biophysics, Director, Vanderbilt Diabetes Center, Vanderbilt University, Nashville, TN, USA

"This book allows you to enjoy an adventurous and instructive guided tour in the archipelago of the islets of Langerhans. A team of expert and enthusiastic explorers will not only conduct the voyager through almost all niches of this complex and fascinating environment, but also provide him with clues and keys for future exploration of still hidden sites". Prof. Pellegrino Masiello, Dept. of Experimental Pathology, University of Pisa, Pisa, Italy.

"The growing prevalence of both type 1 and type 2 diabetes make islet cell biology a critical concern for a wide range of scientists and health professionals. From anatomy and developmental biology, through islet physiology and biochemistry, to issues of immunology and transplantation, this book is a terrific resource". Jonathan M.W.Slack, Ph.D., F.Med.Sci., Director, Stem Cell Institute, University of Minnesota, MTRF, 2001 6th Street SE, Minneapolis, MN 55455, USA

"One will find updated information on almost every essential aspect of islet research in this book including emerging new views on the ultrastructure of rodent and human islets; the fundamentals of nutrient-sensing mechanisms and insights gathered from mathematical modeling; structure/function of islets of animal models of diabetes; immunopathogenesis; and new insights into new potential avenues for clinical intervention. A total of thirty four chapters providing a wealth of information on pancreatic islet structure/function in both physiology and pathology". Pere Santamaria, M.D., Ph.D., Julia McFarlane Diabetes Research Centre, Faculty of Medicine, University of Calgary, 3330 Hospital Dr. N.W., Calgary, Alberta, T2N 4N1, Canada

"It looks very comprehensive and covers all current areas of interest and includes chapters written by world renowned contributors - very nice!". Matthias von Herrath, MD, Professor and Director, Center for Type 1 Diabetes Research, La jolla Institute for Allergy and Immunology

"This book will be welcomed by islet researchers and clinicians interested in the latest developments and theories from which new therapeutics for diabetes can emerge". Martha Pavlakis, MD, Associate Professor of Medicine, Harvard Medical School, Medical Director, Kidney and Pancreas Transplantation, Beth Israel Deaconess Medical Center, Boston, MA

"The field of islet biology is assuming increasing importance with the recognition that b-cell dysfunction is a critical feature of type II diabetes. Improving b-cell function and/or b-cell mass may be the best approach to treating diabetes. Thus, the publication of a book covering so many aspects of this field is timely". Fred Levine, M.D., Ph.D., Professor, Burnham Institute for Medical Research, Director, Sanford Children's Health Research Center

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Chapter 1

AbstractsPosted by Md. Shahidul Islam Wed, October 14, 2009 21:26:17

Microscopic anatomy of the human islets of Langerhans

Peter IN’T VELD and Miriam MARICHAL

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Chapter 2

AbstractsPosted by Md. Shahidul Islam Wed, October 14, 2009 21:24:30

The Comparative Anatomy of Islets

R.Scott Heller

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Chapter 3

AbstractsPosted by Md. Shahidul Islam Wed, October 14, 2009 21:22:21

Approaches for imaging islets: recent advances and future prospects

Ulf Ahlgren & Martin Gotthardt

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Chapter 4

AbstractsPosted by Md. Shahidul Islam Wed, October 14, 2009 21:20:10

Islet cell development

Anabel Rojas, Adrian Khoo, Juan R. Tejedo, Francisco J. Bedoya, Bernat Soria and Franz Martín

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Chapter 5

AbstractsPosted by Md. Shahidul Islam Wed, October 14, 2009 21:17:16

High fat programming of beta cell failure

M.E. Cerf

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Chapter 6

AbstractsPosted by Md. Shahidul Islam Wed, October 14, 2009 21:09:42

Nutrient regulation of insulin secretion and beta cell functional integrity

Philip Newsholme, Celine Gaudel, and Neville H. McClenaghan

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Chapter 7

AbstractsPosted by Md. Shahidul Islam Wed, October 14, 2009 20:57:57

Electrophysiology of islet cells

Gisela Drews*, Peter Krippeit-Drews and Martina Düfer

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